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A Systematic Comparison Identifies an ATP-Based Viability Assay as Most Suitable Read-Out for Drug Screening in Glioma Stem-Like Cells
Serum-free culture methods for patient-derived primary glioma cultures, selecting for glioma stem-like cells (GSCs), are becoming the gold standard in neurooncology research. These GSCs can be implemented in drug screens to detect patient-specific responses, potentially bridging the translational ga...
Autores principales: | Kleijn, A., Kloezeman, J. J., Balvers, R. K., van der Kaaij, M., Dirven, C. M. F., Leenstra, S., Lamfers, M. L. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871979/ https://www.ncbi.nlm.nih.gov/pubmed/27274737 http://dx.doi.org/10.1155/2016/5623235 |
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