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Diabetic foot complicated by vertebral osteomyelitis and epidural abscess

Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with...

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Autores principales: Mantovani, Alessandro, Trombetta, Maddalena, Imbriaco, Chiara, Rigolon, Riccardo, Mingolla, Lucia, Zamboni, Federica, Dal Molin, Francesca, Cioccoloni, Dario, Sanga, Viola, Bruti, Massimiliano, Brocco, Enrico, Conti, Michela, Ravenna, Giorgio, Perrone, Fabrizia, Stoico, Vincenzo, Bonora, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872002/
https://www.ncbi.nlm.nih.gov/pubmed/27252859
http://dx.doi.org/10.1530/EDM-15-0132
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author Mantovani, Alessandro
Trombetta, Maddalena
Imbriaco, Chiara
Rigolon, Riccardo
Mingolla, Lucia
Zamboni, Federica
Dal Molin, Francesca
Cioccoloni, Dario
Sanga, Viola
Bruti, Massimiliano
Brocco, Enrico
Conti, Michela
Ravenna, Giorgio
Perrone, Fabrizia
Stoico, Vincenzo
Bonora, Enzo
author_facet Mantovani, Alessandro
Trombetta, Maddalena
Imbriaco, Chiara
Rigolon, Riccardo
Mingolla, Lucia
Zamboni, Federica
Dal Molin, Francesca
Cioccoloni, Dario
Sanga, Viola
Bruti, Massimiliano
Brocco, Enrico
Conti, Michela
Ravenna, Giorgio
Perrone, Fabrizia
Stoico, Vincenzo
Bonora, Enzo
author_sort Mantovani, Alessandro
collection PubMed
description Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of known infected ulcers in the left foot. Despite intravenous antibiotic treatment and surgical debridement of the foot infection, high fever and lower back pain continued. Bone biopsy and two consecutive blood cultures were positive for Staphylococcus aureus. A spinal magnetic resonance imaging (MRI) was performed, revealing serious osteomyelitis in L4 and L5 complicated by an epidural abscess. Contiguous or other distant focuses of infection were not identified. In this case, diabetic foot could be considered as a primary distant focus for vertebral osteomyelitis. Clinicians should consider vertebral osteomyelitis as a ‘possible’ diagnosis in patients with type 2 diabetes complicated by foot infection that is associated with fever and lower back pain. LEARNING POINTS: Vertebral osteomyelitis is increasing in Western countries, especially in patients with type 2 diabetes. The primary focus of infection is the genitourinary tract followed by skin, soft tissue, endocarditis, bursitis, septic arthritis, and intravascular access. Diabetic foot could be a rare primary focus of infection for vertebral osteomyelitis, and, however, vertebral osteomyelitis could be a serious, albeit rare, complication of diabetic foot. Clinicians should keep in mind the many potential complications of diabetic foot ulcerations and consider vertebral osteomyelitis as a “possible” diagnosis in patients with type 2 diabetes and foot ulcers associated with nonspecific symptoms such as lower back pain. Early diagnosis and correct management of vertebral osteomyelitis are crucial to improve clinical outcomes.
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spelling pubmed-48720022016-06-01 Diabetic foot complicated by vertebral osteomyelitis and epidural abscess Mantovani, Alessandro Trombetta, Maddalena Imbriaco, Chiara Rigolon, Riccardo Mingolla, Lucia Zamboni, Federica Dal Molin, Francesca Cioccoloni, Dario Sanga, Viola Bruti, Massimiliano Brocco, Enrico Conti, Michela Ravenna, Giorgio Perrone, Fabrizia Stoico, Vincenzo Bonora, Enzo Endocrinol Diabetes Metab Case Rep Unique/Unexpected Symptoms or Presentations of a Disease Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of known infected ulcers in the left foot. Despite intravenous antibiotic treatment and surgical debridement of the foot infection, high fever and lower back pain continued. Bone biopsy and two consecutive blood cultures were positive for Staphylococcus aureus. A spinal magnetic resonance imaging (MRI) was performed, revealing serious osteomyelitis in L4 and L5 complicated by an epidural abscess. Contiguous or other distant focuses of infection were not identified. In this case, diabetic foot could be considered as a primary distant focus for vertebral osteomyelitis. Clinicians should consider vertebral osteomyelitis as a ‘possible’ diagnosis in patients with type 2 diabetes complicated by foot infection that is associated with fever and lower back pain. LEARNING POINTS: Vertebral osteomyelitis is increasing in Western countries, especially in patients with type 2 diabetes. The primary focus of infection is the genitourinary tract followed by skin, soft tissue, endocarditis, bursitis, septic arthritis, and intravascular access. Diabetic foot could be a rare primary focus of infection for vertebral osteomyelitis, and, however, vertebral osteomyelitis could be a serious, albeit rare, complication of diabetic foot. Clinicians should keep in mind the many potential complications of diabetic foot ulcerations and consider vertebral osteomyelitis as a “possible” diagnosis in patients with type 2 diabetes and foot ulcers associated with nonspecific symptoms such as lower back pain. Early diagnosis and correct management of vertebral osteomyelitis are crucial to improve clinical outcomes. Bioscientifica Ltd 2016-05-18 2016 /pmc/articles/PMC4872002/ /pubmed/27252859 http://dx.doi.org/10.1530/EDM-15-0132 Text en © 2016 The authors This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en_GB) .
spellingShingle Unique/Unexpected Symptoms or Presentations of a Disease
Mantovani, Alessandro
Trombetta, Maddalena
Imbriaco, Chiara
Rigolon, Riccardo
Mingolla, Lucia
Zamboni, Federica
Dal Molin, Francesca
Cioccoloni, Dario
Sanga, Viola
Bruti, Massimiliano
Brocco, Enrico
Conti, Michela
Ravenna, Giorgio
Perrone, Fabrizia
Stoico, Vincenzo
Bonora, Enzo
Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title_full Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title_fullStr Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title_full_unstemmed Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title_short Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
title_sort diabetic foot complicated by vertebral osteomyelitis and epidural abscess
topic Unique/Unexpected Symptoms or Presentations of a Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872002/
https://www.ncbi.nlm.nih.gov/pubmed/27252859
http://dx.doi.org/10.1530/EDM-15-0132
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