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Diabetic foot complicated by vertebral osteomyelitis and epidural abscess
Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bioscientifica Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872002/ https://www.ncbi.nlm.nih.gov/pubmed/27252859 http://dx.doi.org/10.1530/EDM-15-0132 |
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author | Mantovani, Alessandro Trombetta, Maddalena Imbriaco, Chiara Rigolon, Riccardo Mingolla, Lucia Zamboni, Federica Dal Molin, Francesca Cioccoloni, Dario Sanga, Viola Bruti, Massimiliano Brocco, Enrico Conti, Michela Ravenna, Giorgio Perrone, Fabrizia Stoico, Vincenzo Bonora, Enzo |
author_facet | Mantovani, Alessandro Trombetta, Maddalena Imbriaco, Chiara Rigolon, Riccardo Mingolla, Lucia Zamboni, Federica Dal Molin, Francesca Cioccoloni, Dario Sanga, Viola Bruti, Massimiliano Brocco, Enrico Conti, Michela Ravenna, Giorgio Perrone, Fabrizia Stoico, Vincenzo Bonora, Enzo |
author_sort | Mantovani, Alessandro |
collection | PubMed |
description | Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of known infected ulcers in the left foot. Despite intravenous antibiotic treatment and surgical debridement of the foot infection, high fever and lower back pain continued. Bone biopsy and two consecutive blood cultures were positive for Staphylococcus aureus. A spinal magnetic resonance imaging (MRI) was performed, revealing serious osteomyelitis in L4 and L5 complicated by an epidural abscess. Contiguous or other distant focuses of infection were not identified. In this case, diabetic foot could be considered as a primary distant focus for vertebral osteomyelitis. Clinicians should consider vertebral osteomyelitis as a ‘possible’ diagnosis in patients with type 2 diabetes complicated by foot infection that is associated with fever and lower back pain. LEARNING POINTS: Vertebral osteomyelitis is increasing in Western countries, especially in patients with type 2 diabetes. The primary focus of infection is the genitourinary tract followed by skin, soft tissue, endocarditis, bursitis, septic arthritis, and intravascular access. Diabetic foot could be a rare primary focus of infection for vertebral osteomyelitis, and, however, vertebral osteomyelitis could be a serious, albeit rare, complication of diabetic foot. Clinicians should keep in mind the many potential complications of diabetic foot ulcerations and consider vertebral osteomyelitis as a “possible” diagnosis in patients with type 2 diabetes and foot ulcers associated with nonspecific symptoms such as lower back pain. Early diagnosis and correct management of vertebral osteomyelitis are crucial to improve clinical outcomes. |
format | Online Article Text |
id | pubmed-4872002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Bioscientifica Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48720022016-06-01 Diabetic foot complicated by vertebral osteomyelitis and epidural abscess Mantovani, Alessandro Trombetta, Maddalena Imbriaco, Chiara Rigolon, Riccardo Mingolla, Lucia Zamboni, Federica Dal Molin, Francesca Cioccoloni, Dario Sanga, Viola Bruti, Massimiliano Brocco, Enrico Conti, Michela Ravenna, Giorgio Perrone, Fabrizia Stoico, Vincenzo Bonora, Enzo Endocrinol Diabetes Metab Case Rep Unique/Unexpected Symptoms or Presentations of a Disease Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of known infected ulcers in the left foot. Despite intravenous antibiotic treatment and surgical debridement of the foot infection, high fever and lower back pain continued. Bone biopsy and two consecutive blood cultures were positive for Staphylococcus aureus. A spinal magnetic resonance imaging (MRI) was performed, revealing serious osteomyelitis in L4 and L5 complicated by an epidural abscess. Contiguous or other distant focuses of infection were not identified. In this case, diabetic foot could be considered as a primary distant focus for vertebral osteomyelitis. Clinicians should consider vertebral osteomyelitis as a ‘possible’ diagnosis in patients with type 2 diabetes complicated by foot infection that is associated with fever and lower back pain. LEARNING POINTS: Vertebral osteomyelitis is increasing in Western countries, especially in patients with type 2 diabetes. The primary focus of infection is the genitourinary tract followed by skin, soft tissue, endocarditis, bursitis, septic arthritis, and intravascular access. Diabetic foot could be a rare primary focus of infection for vertebral osteomyelitis, and, however, vertebral osteomyelitis could be a serious, albeit rare, complication of diabetic foot. Clinicians should keep in mind the many potential complications of diabetic foot ulcerations and consider vertebral osteomyelitis as a “possible” diagnosis in patients with type 2 diabetes and foot ulcers associated with nonspecific symptoms such as lower back pain. Early diagnosis and correct management of vertebral osteomyelitis are crucial to improve clinical outcomes. Bioscientifica Ltd 2016-05-18 2016 /pmc/articles/PMC4872002/ /pubmed/27252859 http://dx.doi.org/10.1530/EDM-15-0132 Text en © 2016 The authors This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en_GB) . |
spellingShingle | Unique/Unexpected Symptoms or Presentations of a Disease Mantovani, Alessandro Trombetta, Maddalena Imbriaco, Chiara Rigolon, Riccardo Mingolla, Lucia Zamboni, Federica Dal Molin, Francesca Cioccoloni, Dario Sanga, Viola Bruti, Massimiliano Brocco, Enrico Conti, Michela Ravenna, Giorgio Perrone, Fabrizia Stoico, Vincenzo Bonora, Enzo Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title | Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title_full | Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title_fullStr | Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title_full_unstemmed | Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title_short | Diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
title_sort | diabetic foot complicated by vertebral osteomyelitis and epidural abscess |
topic | Unique/Unexpected Symptoms or Presentations of a Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872002/ https://www.ncbi.nlm.nih.gov/pubmed/27252859 http://dx.doi.org/10.1530/EDM-15-0132 |
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