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Immunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations

OBJECTIVE: We undertook a systems immunology approach of the adaptive immune system in multiple sclerosis (MS), overcoming tradeoffs between scale and level of detail, in order to identify the immunologic signature of MS and the changes wrought by current immunomodulatory treatments. METHODS: We dev...

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Detalles Bibliográficos
Autores principales: Dooley, James, Pauwels, Ine, Franckaert, Dean, Smets, Ide, Garcia-Perez, Josselyn E., Hilven, Kelly, Danso-Abeam, Dina, Terbeek, Joanne, Nguyen, Anh T.L., De Muynck, Louis, Decallonne, Brigitte, Dubois, Bénédicte, Liston, Adrian, Goris, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872020/
https://www.ncbi.nlm.nih.gov/pubmed/27231713
http://dx.doi.org/10.1212/NXI.0000000000000240