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Effective knockdown of Drosophila long non-coding RNAs by CRISPR interference

Long non-coding RNAs (lncRNAs) have emerged as regulators of gene expression across metazoa. Interestingly, some lncRNAs function independently of their transcripts – the transcription of the lncRNA locus itself affects target genes. However, current methods of loss-of-function analysis are insuffic...

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Detalles Bibliográficos
Autores principales:	Ghosh, Sanjay, Tibbit, Charlotte, Liu, Ji-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872081/ https://www.ncbi.nlm.nih.gov/pubmed/26850642 http://dx.doi.org/10.1093/nar/gkw063

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