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Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE
A crucial component of the human mitochondrial DNA replisome is the ring-shaped helicase TWINKLE—a phage T7-gene 4-like protein expressed in the nucleus and localized in the human mitochondria. Our previous studies showed that despite being a helicase, TWINKLE has unique DNA annealing activity. At t...
Autores principales: | Sen, Doyel, Patel, Gayatri, Patel, Smita S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872091/ https://www.ncbi.nlm.nih.gov/pubmed/26887820 http://dx.doi.org/10.1093/nar/gkw098 |
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