Mechanisms of small molecule–DNA interactions probed by single-molecule force spectroscopy

There is a wide range of applications for non-covalent DNA binding ligands, and optimization of such interactions requires detailed understanding of the binding mechanisms. One important class of these ligands is that of intercalators, which bind DNA by inserting aromatic moieties between adjacent D...

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Detalles Bibliográficos
Autores principales: Almaqwashi, Ali A., Paramanathan, Thayaparan, Rouzina, Ioulia, Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872107/
https://www.ncbi.nlm.nih.gov/pubmed/27085806
http://dx.doi.org/10.1093/nar/gkw237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872107/
https://www.ncbi.nlm.nih.gov/pubmed/27085806
http://dx.doi.org/10.1093/nar/gkw237

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