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Mechanisms of small molecule–DNA interactions probed by single-molecule force spectroscopy
There is a wide range of applications for non-covalent DNA binding ligands, and optimization of such interactions requires detailed understanding of the binding mechanisms. One important class of these ligands is that of intercalators, which bind DNA by inserting aromatic moieties between adjacent D...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872107/ https://www.ncbi.nlm.nih.gov/pubmed/27085806 http://dx.doi.org/10.1093/nar/gkw237 |