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Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

The chemically most complex modification in eukaryotic rRNA is the conserved hypermodified nucleotide N1-methyl-N3-aminocarboxypropyl-pseudouridine (m(1)acp(3)Ψ) located next to the P-site tRNA on the small subunit 18S rRNA. While S-adenosylmethionine was identified as the source of the aminocarboxy...

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Detalles Bibliográficos
Autores principales:	Meyer, Britta, Wurm, Jan Philip, Sharma, Sunny, Immer, Carina, Pogoryelov, Denys, Kötter, Peter, Lafontaine, Denis L. J., Wöhnert, Jens, Entian, Karl-Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872110/ https://www.ncbi.nlm.nih.gov/pubmed/27084949 http://dx.doi.org/10.1093/nar/gkw244

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