Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

Formation of nucleosome free region (NFR) accompanied by specific histone modifications at flanking nucleosomes is an important prerequisite for enhancer and promoter activity. Due to this process, active regulatory elements often exhibit a distinct shape of histone signal in the form of a peak-vall...

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Detalles Bibliográficos
Autores principales: Pundhir, Sachin, Bagger, Frederik O., Lauridsen, Felicia B., Rapin, Nicolas, Porse, Bo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872112/
https://www.ncbi.nlm.nih.gov/pubmed/27095194
http://dx.doi.org/10.1093/nar/gkw250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872112/
https://www.ncbi.nlm.nih.gov/pubmed/27095194
http://dx.doi.org/10.1093/nar/gkw250

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