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Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality
Formation of nucleosome free region (NFR) accompanied by specific histone modifications at flanking nucleosomes is an important prerequisite for enhancer and promoter activity. Due to this process, active regulatory elements often exhibit a distinct shape of histone signal in the form of a peak-vall...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872112/ https://www.ncbi.nlm.nih.gov/pubmed/27095194 http://dx.doi.org/10.1093/nar/gkw250 |