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Endocytosis of indium-tin-oxide nanoparticles by macrophages provokes pyroptosis requiring NLRP3-ASC-Caspase1 axis that can be prevented by mesenchymal stem cells
The biological effects of indium-tin-oxide (ITO) are of considerable importance because workers exposed to indium compounds have been diagnosed with interstitial lung disease or pulmonary alveolar proteinosis; however, the pathophysiology of these diseases is undefined. Here, mice intraperitoneally...
Autores principales: | Naji, Abderrahim, Muzembo, Basilua André, Yagyu, Ken-ichi, Baba, Nobuyasu, Deschaseaux, Frédéric, Sensebé, Luc, Suganuma, Narufumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872131/ https://www.ncbi.nlm.nih.gov/pubmed/27194621 http://dx.doi.org/10.1038/srep26162 |
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