The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer

Primary and acquired drug resistance is one of the main obstacles encountered in high-grade serous ovarian cancer (HGSC) chemotherapy. Cisplatin induces DNA damage through cross-linking and long integrated non-coding RNAs (lincRNAs) play an important role in chemical induced DNA-damage response, whi...

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Detalles Bibliográficos
Autores principales: Zheng, Zhi-Guo, Xu, Hong, Suo, Sha-Sha, Xu, Xiao-Li, Ni, Mao-Wei, Gu, Lin-Hui, Chen, Wei, Wang, Liang-Yan, Zhao, Ye, Tian, Bing, Hua, Yue-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872133/
https://www.ncbi.nlm.nih.gov/pubmed/27193186
http://dx.doi.org/10.1038/srep26093

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