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Structural and functional insights into the E3 ligase, RNF126

RNF126 is an E3 ubiquitin ligase that collaborates with the BAG6 sortase complex to ubiquitinate hydrophobic substrates in the cytoplasm that are destined for proteasomal recycling. Composed of a trimeric complex of BAG6, TRC35 and UBL4A the BAG6 sortase is also associated with SGTA, a co-chaperone...

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Detalles Bibliográficos
Autores principales:	Krysztofinska, Ewelina M., Martínez-Lumbreras, Santiago, Thapaliya, Arjun, Evans, Nicola J., High, Stephen, Isaacson, Rivka L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872217/ https://www.ncbi.nlm.nih.gov/pubmed/27193484 http://dx.doi.org/10.1038/srep26433

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