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A rationally engineered yeast pyruvyltransferase Pvg1p introduces sialylation-like properties in neo-human-type complex oligosaccharide

Pyruvylation onto the terminus of oligosaccharide, widely seen from prokaryote to eukaryote, confers negative charges on the cell surface and seems to be functionally similar to sialylation, which is found at the end of human-type complex oligosaccharide. However, detailed molecular mechanisms under...

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Detalles Bibliográficos
Autores principales:	Higuchi, Yujiro, Yoshinaga, Sho, Yoritsune, Ken-ichi, Tateno, Hiroaki, Hirabayashi, Jun, Nakakita, Shin-ichi, Kanekiyo, Miho, Kakuta, Yoshimitsu, Takegawa, Kaoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872226/ https://www.ncbi.nlm.nih.gov/pubmed/27194449 http://dx.doi.org/10.1038/srep26349

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