Enhanced tumor retention of radioiodinated anti-epidermal growth factor receptor antibody using novel bifunctional iodination linker for radioimmunotherapy

Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target tumor cells. Radioiodine is most commonly employed to prepare radiolabeled proteins (antibodies, peptides) for in vitro and in vivo applications. A major shortcoming of radioiodinated pro...

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Detalles Bibliográficos
Autores principales: KIM, EUN JUNG, KIM, BYOUNG SOO, CHOI, DAN BEE, CHI, SUNG-GIL, CHOI, TAE HYUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872277/
https://www.ncbi.nlm.nih.gov/pubmed/27035553
http://dx.doi.org/10.3892/or.2016.4706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872277/
https://www.ncbi.nlm.nih.gov/pubmed/27035553
http://dx.doi.org/10.3892/or.2016.4706

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