Coupling Gd-DTPA with a bispecific, recombinant protein anti-EGFR-iRGD complex improves tumor targeting in MRI

Recombinant anti-epidermal growth factor receptor-internalizing arginine-glycine-aspartic acid (anti-EGFR single-domain antibody fused with iRGD peptide) protein efficiently targets the EGFR extracellular domain and integrin αvβ/β5, and shows a high penetration into cells. Thus, this protein may imp...

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Detalles Bibliográficos
Autores principales: XIN, XIAOYAN, SHA, HUIZI, SHEN, JINGTAO, ZHANG, BING, ZHU, BIN, LIU, BAORUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872280/
https://www.ncbi.nlm.nih.gov/pubmed/27035336
http://dx.doi.org/10.3892/or.2016.4712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872280/
https://www.ncbi.nlm.nih.gov/pubmed/27035336
http://dx.doi.org/10.3892/or.2016.4712

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