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Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801

It has been suggested that a functional deficit in NMDA-receptors (NMDARs) on parvalbumin (PV)-positive interneurons (PV-NMDARs) is central to the pathophysiology of schizophrenia. Supportive evidence come from examination of genetically modified mice where the obligatory NMDAR-subunit GluN1 (also k...

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Detalles Bibliográficos
Autores principales:	Bygrave, A M, Masiulis, S, Nicholson, E, Berkemann, M, Barkus, C, Sprengel, R, Harrison, P J, Kullmann, D M, Bannerman, D M, Kätzel, D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872402/ https://www.ncbi.nlm.nih.gov/pubmed/27070406 http://dx.doi.org/10.1038/tp.2016.44

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