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11β-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse
The identification of new and more effective treatments for alcohol abuse remains a priority. Alcohol intake activates glucocorticoids, which have a key role in alcohol's reinforcing properties. Glucocorticoid effects are modulated in part by the activity of 11β-hydroxysteroid dehydrogenases (1...
Autores principales: | Sanna, P P, Kawamura, T, Chen, J, Koob, G F, Roberts, A J, Vendruscolo, L F, Repunte-Canonigo, V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872439/ https://www.ncbi.nlm.nih.gov/pubmed/26978742 http://dx.doi.org/10.1038/tp.2016.13 |
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