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Reduced sleep duration mediates decreases in striatal D2/D3 receptor availability in cocaine abusers
Neuroimaging studies have documented reduced striatal dopamine D2/D3 receptor (D2/D3R) availability in cocaine abusers, which has been associated with impaired prefrontal activity and vulnerability for relapse. However, the mechanism(s) underlying the decreases in D2/D3R remain poorly understood. Re...
Autores principales: | Wiers, C E, Shumay, E, Cabrera, E, Shokri-Kojori, E, Gladwin, T E, Skarda, E, Cunningham, S I, Kim, S W, Wong, T C, Tomasi, D, Wang, G-J, Volkow, N D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872440/ https://www.ncbi.nlm.nih.gov/pubmed/26954979 http://dx.doi.org/10.1038/tp.2016.14 |
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