Association of thalamic hyperactivity with treatment-resistant depression and poor response in early treatment for major depression: a resting-state fMRI study using fractional amplitude of low-frequency fluctuations

Despite novel antidepressant development, 10–30% of patients with major depressive disorder (MDD) have antidepressant treatment-resistant depression (TRD). Although new therapies are needed, lack of knowledge regarding the neural mechanisms underlying TRD hinders development of new therapeutic optio...

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Detalles Bibliográficos
Autores principales: Yamamura, T, Okamoto, Y, Okada, G, Takaishi, Y, Takamura, M, Mantani, A, Kurata, A, Otagaki, Y, Yamashita, H, Yamawaki, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872444/
https://www.ncbi.nlm.nih.gov/pubmed/26954981
http://dx.doi.org/10.1038/tp.2016.18

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