Cargando…
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness
Robust statistical, genetic and functional evidence supports a role for DISC1 in the aetiology of major mental illness. Furthermore, many of its protein-binding partners show evidence for involvement in the pathophysiology of a range of neurodevelopmental and psychiatric disorders. Copy number varia...
Autores principales: | Johnstone, Mandy, MacLean, Alan, Heyrman, Lien, Lenaerts, An-Sofie, Nordin, Annelie, Nilsson, Lars-Göran, De Rijk, Peter, Goossens, Dirk, Adolfsson, Rolf, Clair, David M. St., Hall, Jeremy, Lawrie, Stephen M., McIntosh, Andrew M., Del-Favero, Jurgen, Blackwood, Douglas H.R., Pickard, Benjamin S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872463/ https://www.ncbi.nlm.nih.gov/pubmed/27239468 http://dx.doi.org/10.1159/000438788 |
Ejemplares similares
-
Sequencing of DISC1 Pathway Genes Reveals Increased Burden of Rare Missense Variants in Schizophrenia Patients from a Northern Swedish Population
por: Moens, Lotte N., et al.
Publicado: (2011) -
The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia
por: Doyle, Orla M., et al.
Publicado: (2015) -
DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness
por: Malavasi, Elise L. V., et al.
Publicado: (2018) -
Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity
por: Whalley, Heather C., et al.
Publicado: (2015) -
Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia
por: Teng, S, et al.
Publicado: (2018)