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Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens
Polymyxins are often last-line therapeutic agents used to treat infections caused by multidrug-resistant A. baumannii. Recent reports of polymyxin-resistant A. baumannii highlight the urgent need for research into mechanisms of polymyxin resistance. This study employed genomic and transcriptomic ana...
Autores principales: | Cheah, Soon-Ee, Johnson, Matthew D., Zhu, Yan, Tsuji, Brian T., Forrest, Alan, Bulitta, Jurgen B., Boyce, John D., Nation, Roger L., Li, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872528/ https://www.ncbi.nlm.nih.gov/pubmed/27195897 http://dx.doi.org/10.1038/srep26233 |
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