Association of Quadriceps Muscle Fat With Isometric Strength Measurements in Healthy Males Using Chemical Shift Encoding-Based Water-Fat Magnetic Resonance Imaging

Magnetic resonance–based assessment of quadriceps muscle fat has been proposed as surrogate marker in sarcopenia, osteoarthritis, and neuromuscular disorders. We presently investigated the association of quadriceps muscle fat with isometric strength measurements in healthy males using chemical shift...

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Detalles Bibliográficos
Autores principales: Baum, Thomas, Inhuber, Stephanie, Dieckmeyer, Michael, Cordes, Christian, Ruschke, Stefan, Klupp, Elisabeth, Jungmann, Pia M., Farlock, Rosanna, Eggers, Holger, Kooijman, Hendrik, Rummeny, Ernst J., Schwirtz, Ansgar, Kirschke, Jan S., Karampinos, Dimitrios C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Musculoskeletal Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872643/
https://www.ncbi.nlm.nih.gov/pubmed/26953765
http://dx.doi.org/10.1097/RCT.0000000000000374
Descripción
Sumario:Magnetic resonance–based assessment of quadriceps muscle fat has been proposed as surrogate marker in sarcopenia, osteoarthritis, and neuromuscular disorders. We presently investigated the association of quadriceps muscle fat with isometric strength measurements in healthy males using chemical shift encoding-based water-fat magnetic resonance imaging. Intermuscular adipose tissue fraction and intramuscular proton density fat fraction correlated significantly (P < 0.05) with isometric strength (up to r = −0.83 and −0.87, respectively). Reproducibility of intermuscular adipose tissue fraction and intramuscular proton density fat fraction was 1.5% and 5.7%, respectively.

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