ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells

Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-l...

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Detalles Bibliográficos
Autores principales: Bian, Ka, Muppani, Naveen Reddy, Elkhadragy, Lobna, Wang, Wei, Zhang, Cheng, Chen, Tenghui, Jung, Sungyun, Seternes, Ole Morten, Long, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://www.ncbi.nlm.nih.gov/pubmed/26701725
http://dx.doi.org/10.18632/oncotarget.6682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://www.ncbi.nlm.nih.gov/pubmed/26701725
http://dx.doi.org/10.18632/oncotarget.6682

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