EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells

Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants and found to have potential anticancer activities. However, the intracellular molecular targets of SLs and the underlying molecular mechanisms have not been well elucidated. In this study, we observed that EM23...

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Detalles Bibliográficos
Autores principales: Shao, Fang-Yuan, Wang, Sheng, Li, Hong-Yu, Chen, Wen-Bo, Wang, Guo-Cai, Ma, Dong-Lei, Wong, Nai Sum, Xiao, Hao, Liu, Qiu-Ying, Zhou, Guang-Xiong, Li, Yao-Lan, Li, Man-Mei, Wang, Yi-Fei, Liu, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872749/
https://www.ncbi.nlm.nih.gov/pubmed/26758418
http://dx.doi.org/10.18632/oncotarget.6828

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