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Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by down-regulating the transcription of CDKN1A

Proteins that contain jumonji C (JmjC) domains have recently been identified as major contributors to various malignant human cancers through epigenetic remodeling. However, the roles of these family members in the pathogenesis of hepatocellular carcinoma (HCC) are obscure. By mining public database...

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Detalles Bibliográficos
Autores principales: Wu, Bing-Hao, Chen, Hui, Cai, Chun-Miao, Fang, Jia-Zhu, Wu, Chong-Chao, Huang, Li-Yu, Wang, Lan, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872753/
https://www.ncbi.nlm.nih.gov/pubmed/26760772
http://dx.doi.org/10.18632/oncotarget.6867