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Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells
Although hypoxia is a prominent feature contributing to the therapeutic resistance of hepatocellular carcinoma cells (HCC) against chemotherapeutic agents, including the Topoisomerase I inhibitor SN38, the underlying mechanism is not fully understood and its understanding remains a major clinical ch...
Autores principales: | Dai, Xiao-Yang, Zhuang, Lin-Han, Wang, Dan-Dan, Zhou, Tian-Yi, Chang, Lin-Lin, Gai, Ren-Hua, Zhu, Di-Feng, Yang, Bo, Zhu, Hong, He, Qiao-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872759/ https://www.ncbi.nlm.nih.gov/pubmed/26771844 http://dx.doi.org/10.18632/oncotarget.6903 |
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