Cargando…

IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer

Interleukin (IL)-32 is a well-known cytokine associated with inflammation, virus infections and cancer. IL-32θ is a newly identified isoform of IL-32, whose function has yet to be elucidated. In this study, we investigated IL-32θ function in colon cancer stem cells. Using samples from colon cancer p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bak, Yesol, Kwon, Taeho, Bak, In seon, Hong, Jintae, Yu, Dae-Yeul, Yoon, Do-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872787/ https://www.ncbi.nlm.nih.gov/pubmed/26824417 http://dx.doi.org/10.18632/oncotarget.7007

Ejemplares similares

IL-32θ inhibits monocytic differentiation of leukemia cells by attenuating expression of transcription factor PU.1
por: Kim, Man Sub, et al.
Publicado: (2015)

A1E reduces stemness and self-renewal in HPV 16-positive cervical cancer stem cells
por: Kwon, Taeho, et al.
Publicado: (2016)

Interleukin-32θ inhibits tumor-promoting effects of macrophage-secreted CCL18 in breast cancer
por: Pham, Thu-Huyen, et al.
Publicado: (2019)

Inhibition of IL-13 and IL-13Rα2 Expression by IL-32θ in Human Monocytic Cells Requires PKCδ and STAT3 Association
por: Pham, Thu-Huyen, et al.
Publicado: (2019)

STK899704 inhibits stemness of cancer stem cells and migration via the FAK-MEK-ERK pathway in HT29 cells
por: Jang, Hui-Ju, et al.
Publicado: (2018)

IL-32θ gene expression in acute myeloid leukemia suppresses TNF-α production
por: Kim, Man Sub, et al.
Publicado: (2015)

Peroxiredoxin I is important for cancer-cell survival in Ras-induced hepatic tumorigenesis
por: Han, Bing, et al.
Publicado: (2016)

BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells
por: Kwon, Taeho, et al.
Publicado: (2018)

MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells
por: Koh, Hyebin, et al.
Publicado: (2017)

Comparison of the Seven Interleukin-32 Isoforms’ Biological Activities: IL-32θ Possesses the Most Dominant Biological Activity
por: Shim, Saerok, et al.
Publicado: (2022)

IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice
por: Ha, Hye-Lin, et al.
Publicado: (2016)

Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification
por: Park, Yun Sun, et al.
Publicado: (2014)

IL-32γ suppresses lung cancer stem cell growth via inhibition of ITGAV-mediated STAT5 pathway
por: Lee, Yong Sun, et al.
Publicado: (2019)

MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells
por: Chandimali, Nisansala, et al.
Publicado: (2018)

Peroxiredoxin II Regulates Cancer Stem Cells and Stemness-Associated Properties of Cancers
por: Chandimali, Nisansala, et al.
Publicado: (2018)

The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer
por: Wang, Shan, et al.
Publicado: (2018)

Interleukin-32θ Triggers Cellular Senescence and Reduces Sensitivity to Doxorubicin-Mediated Cytotoxicity in MDA-MB-231 Cells
por: Pham, Thu-Huyen, et al.
Publicado: (2021)

Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling Pathway
por: Song, Yu Na, et al.
Publicado: (2023)

Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer
por: Xu, Huitao, et al.
Publicado: (2018)

Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling
por: Zhang, Xiaochao, et al.
Publicado: (2018)

Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity
por: Barber, Casey N., et al.
Publicado: (2022)

On θ(ω) continuity
por: Al Ghour, Samer, et al.
Publicado: (2020)

Alterations in IL-6/STAT3 Signaling by Korean Mistletoe Lectin Regulate the Self-Renewal Activity of Placenta-Derived Mesenchymal Stem Cells
por: Kim, Gi Dae, et al.
Publicado: (2019)

Lack of PKCθ Promotes Regenerative Ability of Muscle Stem Cells in Chronic Muscle Injury
por: Fiore, Piera Filomena, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition Associates with Maintenance of Stemness in Spheroid-Derived Stem-Like Colon Cancer Cells
por: Han, Xiao-Yan, et al.
Publicado: (2013)

IL-22 is related to development of human colon cancer by activation of STAT3
por: Jiang, Runqiu, et al.
Publicado: (2013)

IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling
por: Cui, Xiangrong, et al.
Publicado: (2019)

The IL-6–STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression
por: Zhu, Q, et al.
Publicado: (2014)

Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model
por: Yang, Jianying, et al.
Publicado: (2019)

Peripheral Blood-Derived Mesenchymal Stem Cells Modulate Macrophage Plasticity through the IL-10/STAT3 Pathway
por: Pang, Qi-Ming, et al.
Publicado: (2022)

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition
por: Wang, Tung Yuan, et al.
Publicado: (2017)

STAT3, stem cells, cancer stem cells and p63
por: Galoczova, Michaela, et al.
Publicado: (2018)

Research progress of cancer stem cells and IL-6/STAT3 signaling pathway in esophageal adenocarcinoma
por: Chen, Mei, et al.
Publicado: (2020)

Defining the mutation signatures of DNA polymerase θ in cancer genomes
por: Hwang, Taejoo, et al.
Publicado: (2020)

E2F3 accelerates the stemness of colon cancer cells by activating the STAT3 pathway
por: Gao, Qingkun, et al.
Publicado: (2023)

The SRF-YAP-IL6 axis promotes breast cancer stemness
por: Kim, Tackhoon, et al.
Publicado: (2016)

IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals
por: Oh, J H, et al.
Publicado: (2011)

An answer to colon cancer treatment by mesenchymal stem cell originated from adipose tissue
por: Iplik, Elif Sinem, et al.
Publicado: (2018)

BRM270 targets cancer stem cells and augments chemo-sensitivity in cancer
por: Chandimali, Nisansala, et al.
Publicado: (2020)

TNF+ regulatory T cells regulate the stemness of gastric cancer cells through the IL13/STAT3 pathway
por: Zhao, Rou, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qab9lu5nmieuag92jcjv6ctaa6