Cargando…

Advances in the use of nanocarriers for cancer diagnosis and treatment

The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attrac...

Descripción completa

Detalles Bibliográficos
Autores principales: Vieira, Débora Braga, Gamarra, Lionel Fernel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872924/
https://www.ncbi.nlm.nih.gov/pubmed/27074238
http://dx.doi.org/10.1590/S1679-45082016RB3475
_version_ 1782432800618577920
author Vieira, Débora Braga
Gamarra, Lionel Fernel
author_facet Vieira, Débora Braga
Gamarra, Lionel Fernel
author_sort Vieira, Débora Braga
collection PubMed
description The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy.
format Online
Article
Text
id pubmed-4872924
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Instituto Israelita de Ensino e Pesquisa Albert Einstein
record_format MEDLINE/PubMed
spelling pubmed-48729242016-08-10 Advances in the use of nanocarriers for cancer diagnosis and treatment Vieira, Débora Braga Gamarra, Lionel Fernel Einstein (Sao Paulo) Reviewing Basic Sciences The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy. Instituto Israelita de Ensino e Pesquisa Albert Einstein 2016 /pmc/articles/PMC4872924/ /pubmed/27074238 http://dx.doi.org/10.1590/S1679-45082016RB3475 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviewing Basic Sciences
Vieira, Débora Braga
Gamarra, Lionel Fernel
Advances in the use of nanocarriers for cancer diagnosis and treatment
title Advances in the use of nanocarriers for cancer diagnosis and treatment
title_full Advances in the use of nanocarriers for cancer diagnosis and treatment
title_fullStr Advances in the use of nanocarriers for cancer diagnosis and treatment
title_full_unstemmed Advances in the use of nanocarriers for cancer diagnosis and treatment
title_short Advances in the use of nanocarriers for cancer diagnosis and treatment
title_sort advances in the use of nanocarriers for cancer diagnosis and treatment
topic Reviewing Basic Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872924/
https://www.ncbi.nlm.nih.gov/pubmed/27074238
http://dx.doi.org/10.1590/S1679-45082016RB3475
work_keys_str_mv AT vieiradeborabraga advancesintheuseofnanocarriersforcancerdiagnosisandtreatment
AT gamarralionelfernel advancesintheuseofnanocarriersforcancerdiagnosisandtreatment