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Advances in the use of nanocarriers for cancer diagnosis and treatment
The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attrac...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Israelita de Ensino e Pesquisa Albert Einstein
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872924/ https://www.ncbi.nlm.nih.gov/pubmed/27074238 http://dx.doi.org/10.1590/S1679-45082016RB3475 |
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author | Vieira, Débora Braga Gamarra, Lionel Fernel |
author_facet | Vieira, Débora Braga Gamarra, Lionel Fernel |
author_sort | Vieira, Débora Braga |
collection | PubMed |
description | The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy. |
format | Online Article Text |
id | pubmed-4872924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
record_format | MEDLINE/PubMed |
spelling | pubmed-48729242016-08-10 Advances in the use of nanocarriers for cancer diagnosis and treatment Vieira, Débora Braga Gamarra, Lionel Fernel Einstein (Sao Paulo) Reviewing Basic Sciences The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy. Instituto Israelita de Ensino e Pesquisa Albert Einstein 2016 /pmc/articles/PMC4872924/ /pubmed/27074238 http://dx.doi.org/10.1590/S1679-45082016RB3475 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviewing Basic Sciences Vieira, Débora Braga Gamarra, Lionel Fernel Advances in the use of nanocarriers for cancer diagnosis and treatment |
title | Advances in the use of nanocarriers for cancer diagnosis and treatment |
title_full | Advances in the use of nanocarriers for cancer diagnosis and treatment |
title_fullStr | Advances in the use of nanocarriers for cancer diagnosis and treatment |
title_full_unstemmed | Advances in the use of nanocarriers for cancer diagnosis and treatment |
title_short | Advances in the use of nanocarriers for cancer diagnosis and treatment |
title_sort | advances in the use of nanocarriers for cancer diagnosis and treatment |
topic | Reviewing Basic Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872924/ https://www.ncbi.nlm.nih.gov/pubmed/27074238 http://dx.doi.org/10.1590/S1679-45082016RB3475 |
work_keys_str_mv | AT vieiradeborabraga advancesintheuseofnanocarriersforcancerdiagnosisandtreatment AT gamarralionelfernel advancesintheuseofnanocarriersforcancerdiagnosisandtreatment |