Cargando…
ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production
ATP-binding cassette G1 (ABCG1) and ABCG4, expressed in neurons and glia in the central nervous system, mediate cholesterol efflux to lipid acceptors. The relationship between cholesterol level in the central nervous system and Alzheimer’s disease has been reported. In this study, we examined the ef...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872999/ https://www.ncbi.nlm.nih.gov/pubmed/27196068 http://dx.doi.org/10.1371/journal.pone.0155400 |