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The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey

OBJECTIVE: The Roma minority represents the largest ethnic group in Central and South-East European countries. Data regarding the mortality in Roma hemodialysis subjects are limited. We evaluated the 3 year mortality of ESRD Roma patients treated with hemodialysis (HD). STUDY DESIGN AND SETTING: Our...

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Autores principales: Gadalean, Florica, Lighezan, Daniel, Stoian, Dana, Schiller, Oana, Timar, Romulus, Timar, Bogdan, Bob, Flaviu, Donciu, Mihaela Dora, Munteanu, Mircea, Mihaescu, Adelina, Covic, Adrian, Schiller, Adalbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873236/
https://www.ncbi.nlm.nih.gov/pubmed/27196564
http://dx.doi.org/10.1371/journal.pone.0155271
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author Gadalean, Florica
Lighezan, Daniel
Stoian, Dana
Schiller, Oana
Timar, Romulus
Timar, Bogdan
Bob, Flaviu
Donciu, Mihaela Dora
Munteanu, Mircea
Mihaescu, Adelina
Covic, Adrian
Schiller, Adalbert
author_facet Gadalean, Florica
Lighezan, Daniel
Stoian, Dana
Schiller, Oana
Timar, Romulus
Timar, Bogdan
Bob, Flaviu
Donciu, Mihaela Dora
Munteanu, Mircea
Mihaescu, Adelina
Covic, Adrian
Schiller, Adalbert
author_sort Gadalean, Florica
collection PubMed
description OBJECTIVE: The Roma minority represents the largest ethnic group in Central and South-East European countries. Data regarding the mortality in Roma hemodialysis subjects are limited. We evaluated the 3 year mortality of ESRD Roma patients treated with hemodialysis (HD). STUDY DESIGN AND SETTING: Our prospective cohort study included 600 ESRD patients on HD therapy recruited from 7 HD centers, from the main geographical regions of Romania. The median age of the patients was 56 (19) years, 332 (55.3%) being males, 51 (8.5%) having Roma ethnicity. RESULTS: Roma ESRD patients initiate dialysis at a younger age, 47.8 years vs. 52.3 years (P = 0.017), present higher serum albumin (P = 0.013) and higher serum phosphate levels (P = 0.021). In the Roma group, the overall 3 year mortality was higher when compared to Caucasians (33.3% vs. 24.8%). The multivariate survival analysis revealed that being of Roma ethnicity is an independent risk factor for mortality (HR = 1.74; 95% CI = 1.04–2.91; P = 0.035). CONCLUSIONS: Roma patients with ESRD initiate HD therapy at a younger age as compared to Caucasians. They have a higher 3 year mortality rate and are dying at a younger age. Roma ethnicity represents an independent risk factor for mortality in our cohort.
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spelling pubmed-48732362016-06-09 The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey Gadalean, Florica Lighezan, Daniel Stoian, Dana Schiller, Oana Timar, Romulus Timar, Bogdan Bob, Flaviu Donciu, Mihaela Dora Munteanu, Mircea Mihaescu, Adelina Covic, Adrian Schiller, Adalbert PLoS One Research Article OBJECTIVE: The Roma minority represents the largest ethnic group in Central and South-East European countries. Data regarding the mortality in Roma hemodialysis subjects are limited. We evaluated the 3 year mortality of ESRD Roma patients treated with hemodialysis (HD). STUDY DESIGN AND SETTING: Our prospective cohort study included 600 ESRD patients on HD therapy recruited from 7 HD centers, from the main geographical regions of Romania. The median age of the patients was 56 (19) years, 332 (55.3%) being males, 51 (8.5%) having Roma ethnicity. RESULTS: Roma ESRD patients initiate dialysis at a younger age, 47.8 years vs. 52.3 years (P = 0.017), present higher serum albumin (P = 0.013) and higher serum phosphate levels (P = 0.021). In the Roma group, the overall 3 year mortality was higher when compared to Caucasians (33.3% vs. 24.8%). The multivariate survival analysis revealed that being of Roma ethnicity is an independent risk factor for mortality (HR = 1.74; 95% CI = 1.04–2.91; P = 0.035). CONCLUSIONS: Roma patients with ESRD initiate HD therapy at a younger age as compared to Caucasians. They have a higher 3 year mortality rate and are dying at a younger age. Roma ethnicity represents an independent risk factor for mortality in our cohort. Public Library of Science 2016-05-19 /pmc/articles/PMC4873236/ /pubmed/27196564 http://dx.doi.org/10.1371/journal.pone.0155271 Text en © 2016 Gadalean et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Gadalean, Florica
Lighezan, Daniel
Stoian, Dana
Schiller, Oana
Timar, Romulus
Timar, Bogdan
Bob, Flaviu
Donciu, Mihaela Dora
Munteanu, Mircea
Mihaescu, Adelina
Covic, Adrian
Schiller, Adalbert
The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title_full The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title_fullStr The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title_full_unstemmed The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title_short The Survival of Roma Minority Patients on Chronic Hemodialysis Therapy - A Romanian Multicenter Survey
title_sort survival of roma minority patients on chronic hemodialysis therapy - a romanian multicenter survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873236/
https://www.ncbi.nlm.nih.gov/pubmed/27196564
http://dx.doi.org/10.1371/journal.pone.0155271
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