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An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010
Disparities in Cervical Cancer (CC) mortality outcomes between African American (AA) and White women have been studied for decades. However, conclusions about the effect of race on CC survival differ across studies. This study assessed differences in CC survival between AA and White women diagnosed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873605/ https://www.ncbi.nlm.nih.gov/pubmed/27185053 http://dx.doi.org/10.1002/cam4.765 |
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author | Weragoda, Janaka Azuero, Andres Badiga, Suguna Bell, Walter C. Matthews, Roland Piyathilake, Chandrika |
author_facet | Weragoda, Janaka Azuero, Andres Badiga, Suguna Bell, Walter C. Matthews, Roland Piyathilake, Chandrika |
author_sort | Weragoda, Janaka |
collection | PubMed |
description | Disparities in Cervical Cancer (CC) mortality outcomes between African American (AA) and White women have been studied for decades. However, conclusions about the effect of race on CC survival differ across studies. This study assessed differences in CC survival between AA and White women diagnosed between 1985 and 2010 and treated at two major hospitals in the southeastern US. The study sample included 925 AA and 1192 White women diagnosed with cervical adenocarcinoma, adenosquamous cell carcinoma, or squamous cell carcinoma. Propensity score adjustment and matching were employed to compare 5‐year survival between the two racial groups. Crude comparisons suggested relevant racial differences in survival. However, the racial differences became of small magnitude after propensity‐score adjustment and in matched analyses. Nonlinear models identified age at diagnosis, cancer stage, mode of treatment, and histological subtype as the most salient characteristics predicting 5‐year survival of CC, yet these characteristics were also associated with race. Crude racial differences in survival might be partly explained by underlying differences in the characteristics of racial groups, such as age at diagnosis, histological subtype, cancer stage, and the mode of treatment. The study results highlight the need to improve access to early screening and treatment opportunities for AA women to improve posttreatment survival from CC. |
format | Online Article Text |
id | pubmed-4873605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48736052016-06-02 An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 Weragoda, Janaka Azuero, Andres Badiga, Suguna Bell, Walter C. Matthews, Roland Piyathilake, Chandrika Cancer Med Cancer Prevention Disparities in Cervical Cancer (CC) mortality outcomes between African American (AA) and White women have been studied for decades. However, conclusions about the effect of race on CC survival differ across studies. This study assessed differences in CC survival between AA and White women diagnosed between 1985 and 2010 and treated at two major hospitals in the southeastern US. The study sample included 925 AA and 1192 White women diagnosed with cervical adenocarcinoma, adenosquamous cell carcinoma, or squamous cell carcinoma. Propensity score adjustment and matching were employed to compare 5‐year survival between the two racial groups. Crude comparisons suggested relevant racial differences in survival. However, the racial differences became of small magnitude after propensity‐score adjustment and in matched analyses. Nonlinear models identified age at diagnosis, cancer stage, mode of treatment, and histological subtype as the most salient characteristics predicting 5‐year survival of CC, yet these characteristics were also associated with race. Crude racial differences in survival might be partly explained by underlying differences in the characteristics of racial groups, such as age at diagnosis, histological subtype, cancer stage, and the mode of treatment. The study results highlight the need to improve access to early screening and treatment opportunities for AA women to improve posttreatment survival from CC. John Wiley and Sons Inc. 2016-05-17 /pmc/articles/PMC4873605/ /pubmed/27185053 http://dx.doi.org/10.1002/cam4.765 Text en © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cancer Prevention Weragoda, Janaka Azuero, Andres Badiga, Suguna Bell, Walter C. Matthews, Roland Piyathilake, Chandrika An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title | An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title_full | An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title_fullStr | An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title_full_unstemmed | An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title_short | An examination of racial differences in 5‐year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010 |
title_sort | examination of racial differences in 5‐year survival of cervical cancer among african american and white american women in the southeastern us from 1985 to 2010 |
topic | Cancer Prevention |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873605/ https://www.ncbi.nlm.nih.gov/pubmed/27185053 http://dx.doi.org/10.1002/cam4.765 |
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