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Dietary salt regulates uroguanylin expression and signaling activity in the kidney, but not in the intestine
The peptide uroguanylin (Ugn) is expressed at significant levels only in intestine and kidney, and is stored in both tissues primarily (perhaps exclusively) as intact prouroguanylin (proUgn). Intravascular infusion of either Ugn or proUgn evokes well‐characterized natriuretic responses in rodents. F...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873633/ https://www.ncbi.nlm.nih.gov/pubmed/27185905 http://dx.doi.org/10.14814/phy2.12782 |