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The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes
A subset of inflammatory-response NF-κB target genes is activated immediately following pro-inflammatory signal. Here we followed the kinetics of primary transcript accumulation after NF-κB activation when the elongation factor Spt5 is knocked down. While elongation rate is unchanged, the transcript...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873663/ https://www.ncbi.nlm.nih.gov/pubmed/27180651 http://dx.doi.org/10.1038/ncomms11547 |