ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation

The ERK1/2 MAPK signalling module integrates extracellular cues that induce proliferation and differentiation of epithelial lineages, and is an established oncogenic driver, particularly in the intestine. However, the interrelation of the ERK1/2 module relative to other signalling pathways in intest...

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Detalles Bibliográficos
Autores principales: de Jong, Petrus R., Taniguchi, Koji, Harris, Alexandra R., Bertin, Samuel, Takahashi, Naoki, Duong, Jen, Campos, Alejandro D., Powis, Garth, Corr, Maripat, Karin, Michael, Raz, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873670/
https://www.ncbi.nlm.nih.gov/pubmed/27187615
http://dx.doi.org/10.1038/ncomms11551

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