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Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report

INTRODUCTION: Phyllodes tumour (PT) is a rare tumour of the female breast. The tumour clinically and radiologically mimics the features of a fibroadenoma. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is a very rare finding. PRESENTATION OF CASE: We present youngest ever case of...

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Detalles Bibliográficos
Autores principales: Chopra, Sharat, Muralikrishnan, Vummiti, Brotto, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873689/
https://www.ncbi.nlm.nih.gov/pubmed/27186962
http://dx.doi.org/10.1016/j.ijscr.2016.04.053
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author Chopra, Sharat
Muralikrishnan, Vummiti
Brotto, Maurizio
author_facet Chopra, Sharat
Muralikrishnan, Vummiti
Brotto, Maurizio
author_sort Chopra, Sharat
collection PubMed
description INTRODUCTION: Phyllodes tumour (PT) is a rare tumour of the female breast. The tumour clinically and radiologically mimics the features of a fibroadenoma. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is a very rare finding. PRESENTATION OF CASE: We present youngest ever case of a 23-year-old nulliparous woman with high-grade ductal carcinoma in situ arising within a benign phyllodes tumor. Macroscopically, it is a homogeneous tumour with solid components. Microscopically, it features typical leaf-like pattern with hypercellular stroma with high-grade ductal carcinoma in situ. DISCUSSION: To date, eight such rare cases of benign phyllodes tumour with ductal carcinoma in situ have been documented. We report the youngest case known in literature so far. CONCLUSION: As this is a very rare presentation, it poses several challenges in regard to both management and follow-up.
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spelling pubmed-48736892016-05-24 Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report Chopra, Sharat Muralikrishnan, Vummiti Brotto, Maurizio Int J Surg Case Rep Case Report INTRODUCTION: Phyllodes tumour (PT) is a rare tumour of the female breast. The tumour clinically and radiologically mimics the features of a fibroadenoma. Ductal carcinoma in situ (DCIS) in the epithelial component of PT is a very rare finding. PRESENTATION OF CASE: We present youngest ever case of a 23-year-old nulliparous woman with high-grade ductal carcinoma in situ arising within a benign phyllodes tumor. Macroscopically, it is a homogeneous tumour with solid components. Microscopically, it features typical leaf-like pattern with hypercellular stroma with high-grade ductal carcinoma in situ. DISCUSSION: To date, eight such rare cases of benign phyllodes tumour with ductal carcinoma in situ have been documented. We report the youngest case known in literature so far. CONCLUSION: As this is a very rare presentation, it poses several challenges in regard to both management and follow-up. Elsevier 2016-05-06 /pmc/articles/PMC4873689/ /pubmed/27186962 http://dx.doi.org/10.1016/j.ijscr.2016.04.053 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chopra, Sharat
Muralikrishnan, Vummiti
Brotto, Maurizio
Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title_full Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title_fullStr Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title_full_unstemmed Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title_short Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: A case report
title_sort youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873689/
https://www.ncbi.nlm.nih.gov/pubmed/27186962
http://dx.doi.org/10.1016/j.ijscr.2016.04.053
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AT brottomaurizio youngestcaseofductalcarcinomainsituarisingwithinabenignphyllodestumouracasereport