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Fast MS/MS acquisition without dynamic exclusion enables precise and accurate quantification of proteome by MS/MS fragment intensity

Most currently proteomic studies use data-dependent acquisition with dynamic exclusion to identify and quantify the peptides generated by the digestion of biological sample. Although dynamic exclusion permits more identifications and higher possibility to find low abundant proteins, stochastic and i...

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Detalles Bibliográficos
Autores principales: Zhang, Shen, Wu, Qi, Shan, Yichu, Zhao, Qun, Zhao, Baofeng, Weng, Yejing, Sui, Zhigang, Zhang, Lihua, Zhang, Yukui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873735/
https://www.ncbi.nlm.nih.gov/pubmed/27198003
http://dx.doi.org/10.1038/srep26392

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