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Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism
Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873740/ https://www.ncbi.nlm.nih.gov/pubmed/27198160 http://dx.doi.org/10.1038/srep26395 |
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author | Di Giorgio, Elisa Frasnelli, Elisa Rosa Salva, Orsola Maria Luisa, Scattoni Puopolo, Maria Tosoni, Daniela Simion, Francesca Vallortigara, Giorgio |
author_facet | Di Giorgio, Elisa Frasnelli, Elisa Rosa Salva, Orsola Maria Luisa, Scattoni Puopolo, Maria Tosoni, Daniela Simion, Francesca Vallortigara, Giorgio |
author_sort | Di Giorgio, Elisa |
collection | PubMed |
description | Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis is that autism is usually not diagnosed until a child is at least 3 years old. Here, we circumvented this difficulty by studying for the very first time, the predispositions to pay attention to social stimuli in newborns with a high familial risk of autism. Results showed that visual preferences to social stimuli strikingly differed between high-risk and low-risk newborns. Significant predictors for high-risk newborns were obtained and an accurate biomarker was identified. The results revealed early behavioural characteristics of newborns with familial risk for ASD, allowing for a prospective approach to the emergence of autism in early infancy. |
format | Online Article Text |
id | pubmed-4873740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48737402016-06-02 Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism Di Giorgio, Elisa Frasnelli, Elisa Rosa Salva, Orsola Maria Luisa, Scattoni Puopolo, Maria Tosoni, Daniela Simion, Francesca Vallortigara, Giorgio Sci Rep Article Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis is that autism is usually not diagnosed until a child is at least 3 years old. Here, we circumvented this difficulty by studying for the very first time, the predispositions to pay attention to social stimuli in newborns with a high familial risk of autism. Results showed that visual preferences to social stimuli strikingly differed between high-risk and low-risk newborns. Significant predictors for high-risk newborns were obtained and an accurate biomarker was identified. The results revealed early behavioural characteristics of newborns with familial risk for ASD, allowing for a prospective approach to the emergence of autism in early infancy. Nature Publishing Group 2016-05-20 /pmc/articles/PMC4873740/ /pubmed/27198160 http://dx.doi.org/10.1038/srep26395 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Di Giorgio, Elisa Frasnelli, Elisa Rosa Salva, Orsola Maria Luisa, Scattoni Puopolo, Maria Tosoni, Daniela Simion, Francesca Vallortigara, Giorgio Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title | Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title_full | Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title_fullStr | Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title_full_unstemmed | Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title_short | Difference in Visual Social Predispositions Between Newborns at Low- and High-risk for Autism |
title_sort | difference in visual social predispositions between newborns at low- and high-risk for autism |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873740/ https://www.ncbi.nlm.nih.gov/pubmed/27198160 http://dx.doi.org/10.1038/srep26395 |
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