Novel positive allosteric modulators of GABA(A) receptors with anesthetic activity

GABA(A) receptors are the main inhibitory neurotransmitter receptors in the brain and are targets for numerous clinically important drugs such as benzodiazepines, anxiolytics and anesthetics. We previously identified novel ligands of the classical benzodiazepine binding pocket in α(1)β(2)γ(2) GABA(A...

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Detalles Bibliográficos
Autores principales: Maldifassi, Maria C., Baur, Roland, Pierce, David, Nourmahnad, Anahita, Forman, Stuart A., Sigel, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873749/
https://www.ncbi.nlm.nih.gov/pubmed/27198062
http://dx.doi.org/10.1038/srep25943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873749/
https://www.ncbi.nlm.nih.gov/pubmed/27198062
http://dx.doi.org/10.1038/srep25943

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