Cargando…

Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway

Piperlongumine has anti-cancer activity in numerous cancer cell lines via various signaling pathways. But there has been no study regarding the mechanisms of PL on the lung cancer yet. Thus, we evaluated the anti-cancer effects and possible mechanisms of PL on non-small cell lung cancer (NSCLC) cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Jie, Son, Dong Ju, Gu, Sun Mi, Woo, Ju Rang, Ham, Young Wan, Lee, Hee Pom, Kim, Wun Jae, Jung, Jae Kyung, Hong, Jin Tae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873819/ https://www.ncbi.nlm.nih.gov/pubmed/27198178 http://dx.doi.org/10.1038/srep26357

Ejemplares similares

Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
por: Gu, Sun Mi, et al.
Publicado: (2018)

MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain
por: Son, Dong Ju, et al.
Publicado: (2017)

Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B
por: Zheng, Jie, et al.
Publicado: (2015)

Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway
por: Gu, Sun Mi, et al.
Publicado: (2015)

A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals
por: Lee, Yong Sun, et al.
Publicado: (2021)

K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway
por: Ham, Hyeon Joo, et al.
Publicado: (2020)

Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo
por: Spiller, Susan E, et al.
Publicado: (2011)

Simvastatin Reduces Lipopolysaccharides-Accelerated Cerebral Ischemic Injury via Inhibition of Nuclear Factor-kappa B Activity
por: Anthony Jalin, Angela M. A., et al.
Publicado: (2015)

The dichotomy of inhibiting nuclear factor kappa-B in pneumonia
por: Abraham, Edward
Publicado: (2013)

Orally Administrated Lactobacillus pentosus var. plantarum C29 Ameliorates Age-Dependent Colitis by Inhibiting the Nuclear Factor-Kappa B Signaling Pathway via the Regulation of Lipopolysaccharide Production by Gut Microbiota
por: Jeong, Jin-Ju, et al.
Publicado: (2015)

Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo
por: Park, Sang Mi, et al.
Publicado: (2018)

Preformulation Studies on Piperlongumine
por: Aodah, Alhassan, et al.
Publicado: (2016)

On the Inhibition Mechanism of Glutathione Transferase P1 by Piperlongumine. Insight From Theory
por: Prejanò, Mario, et al.
Publicado: (2018)

Correction: Orally Administrated Lactobacillus pentosus var. plantarum C29 Ameliorates Age-Dependent Colitis by Inhibiting the Nuclear Factor-Kappa B Signaling Pathway via the Regulation of Lipopolysaccharide Production by Gut Microbiota
por: Jeong, Jin-Ju, et al.
Publicado: (2015)

Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
por: Chen, Yong, et al.
Publicado: (2015)

Novel synthetic (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol inhibits arthritis by targeting signal transducer and activator of transcription 3
por: Son, Dong Ju, et al.
Publicado: (2016)

Piperlongumine Inhibits Migration of Glioblastoma Cells via Activation of ROS-Dependent p38 and JNK Signaling Pathways
por: Liu, Qian Rong, et al.
Publicado: (2014)

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models
por: Lee, Young-Jung, et al.
Publicado: (2012)

A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer in vivo and in vitro
por: Zheng, Jie, et al.
Publicado: (2017)

Inhibition of the Expression of Matrix Metalloproteinases in Articular Chondrocytes by Resveratrol through Affecting Nuclear Factor-Kappa B Signaling Pathway
por: Kang, Dong-Geun, et al.
Publicado: (2018)

Metabolic profile and safety of piperlongumine
por: de Lima Moreira, Fernanda, et al.
Publicado: (2016)

G721-0282 Exerts Anxiolytic-Like Effects on Chronic Unpredictable Mild Stress in Mice Through Inhibition of Chitinase-3-Like 1-Mediated Neuroinflammation
por: Ham, Hyeon Joo, et al.
Publicado: (2022)

Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice
por: Go, Jun, et al.
Publicado: (2018)

Natural product piperlongumine inhibits proliferation of oral squamous carcinoma cells by inducing ferroptosis and inhibiting intracellular antioxidant capacity
por: Wang, Zi-Qian, et al.
Publicado: (2022)

Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion
por: Bauerle, Kevin T, et al.
Publicado: (2010)

Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin
por: Jeon, Seong Hee, et al.
Publicado: (2021)

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells
por: Yao, Yao, et al.
Publicado: (2016)

Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways
por: Liu, Xuan, et al.
Publicado: (2022)

Piperlongumine Inhibits Thioredoxin Reductase 1 by Targeting Selenocysteine Residues and Sensitizes Cancer Cells to Erastin
por: Yang, Yijia, et al.
Publicado: (2022)

Synergistic Inhibitory Effects of Cetuximab and Cisplatin on Human Colon Cancer Cell Growth via Inhibition of the ERK-Dependent EGF Receptor Signaling Pathway
por: Son, Dong Ju, et al.
Publicado: (2015)

(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice
por: Zheng, Jie, et al.
Publicado: (2015)

Piperlongumine-Eluting Gastrointestinal Stent Using Reactive Oxygen Species-Sensitive Nanofiber Mats for Inhibition of Cholangiocarcinoma Cells
por: Jang, Hyung Ha, et al.
Publicado: (2019)

Identification of Piperlongumine as Potent Inhibitor of Necroptosis
por: He, Xiaoyan, et al.
Publicado: (2023)

How to Inhibit Nuclear Factor-Kappa B Signaling: Lessons from Poxviruses
por: Reus, Joshua B., et al.
Publicado: (2022)

Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells
por: Jung, Chang Hee, et al.
Publicado: (2014)

(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates LPS-Mediated Memory Impairment by Inhibition of STAT3 Pathway
por: Choi, Ji Yeon, et al.
Publicado: (2017)

Baicalin attenuates lipopolysaccharide-induced neuroinflammation in cerebral cortex of mice via inhibiting nuclear factor kappa B (NF-κB) activation
por: SHAH, Murad-Ali, et al.
Publicado: (2019)

Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death
por: Makhov, P, et al.
Publicado: (2014)

Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation
por: Thatikonda, Sowjanya, et al.
Publicado: (2020)

Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction
por: Cheon, So Yeong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ed90ecp3me720sl38vtnhrqo4h