Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice

Men have worse survival than premenopausal women after intracerebral hemorrhage (ICH). After ICH, overproduction of iron associated with induction of heme oxygenase-1 (HO-1) in brain was observed. Rodent ICH model using ferrous citrate (FC)-infusion into the striatum to simulate iron overload, showe...

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Detalles Bibliográficos
Autores principales: Wang, Li-Fang, Yokoyama, Kazunari K., Lin, Chih-Lung, Chen, Tzu-Yin, Hsiao, Hsiu-Wen, Chiang, Pei-Chi, Hsu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873828/
https://www.ncbi.nlm.nih.gov/pubmed/27198537
http://dx.doi.org/10.1038/srep26358

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