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Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines

This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. With only limited high-level evidence for management of nasal and paranasal sinus cancers owing to low incidence and diverse histology, this paper provides recommend...

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Autores principales: Lund, V J, Clarke, P M, Swift, A C, McGarry, G W, Kerawala, C, Carnell, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873911/
https://www.ncbi.nlm.nih.gov/pubmed/27841122
http://dx.doi.org/10.1017/S0022215116000530
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author Lund, V J
Clarke, P M
Swift, A C
McGarry, G W
Kerawala, C
Carnell, D
author_facet Lund, V J
Clarke, P M
Swift, A C
McGarry, G W
Kerawala, C
Carnell, D
author_sort Lund, V J
collection PubMed
description This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. With only limited high-level evidence for management of nasal and paranasal sinus cancers owing to low incidence and diverse histology, this paper provides recommendations on the work up and management based on the existing evidence base. RECOMMENDATIONS: • Sinonasal tumours are best treated de novo and unusual polyps should be imaged and biopsied prior to definitive surgery. (G) • Treatment of sinonasal malignancy should be carefully planned and discussed at a specialist skull base multidisciplinary team meeting with all relevant expertise. (G) • Complete surgical resection is the mainstay of treatment for inverted papilloma and juvenile angiofibroma. (R) • Essential equipment is necessary and must be available prior to commencing endonasal resection of skull base malignancy. (G) • Endoscopic skull base surgery may be facilitated by two surgeons working simultaneously, utilising both sides of the nose. (G) • To ensure the optimum oncological results, the primary tumour must be completely removed and margins checked by frozen section if necessary. (G) • The most common management approach is surgery followed by post-operative radiotherapy, ideally within six weeks. (R) • Radiation is given first if a response to radiation may lead to organ preservation. (G) • Radiotherapy should be delivered within an accredited department using megavoltage photons from a linear accelerator (typical energies 4–6 MV) as an unbroken course. (R)
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spelling pubmed-48739112016-05-27 Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines Lund, V J Clarke, P M Swift, A C McGarry, G W Kerawala, C Carnell, D J Laryngol Otol Guidelines This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. With only limited high-level evidence for management of nasal and paranasal sinus cancers owing to low incidence and diverse histology, this paper provides recommendations on the work up and management based on the existing evidence base. RECOMMENDATIONS: • Sinonasal tumours are best treated de novo and unusual polyps should be imaged and biopsied prior to definitive surgery. (G) • Treatment of sinonasal malignancy should be carefully planned and discussed at a specialist skull base multidisciplinary team meeting with all relevant expertise. (G) • Complete surgical resection is the mainstay of treatment for inverted papilloma and juvenile angiofibroma. (R) • Essential equipment is necessary and must be available prior to commencing endonasal resection of skull base malignancy. (G) • Endoscopic skull base surgery may be facilitated by two surgeons working simultaneously, utilising both sides of the nose. (G) • To ensure the optimum oncological results, the primary tumour must be completely removed and margins checked by frozen section if necessary. (G) • The most common management approach is surgery followed by post-operative radiotherapy, ideally within six weeks. (R) • Radiation is given first if a response to radiation may lead to organ preservation. (G) • Radiotherapy should be delivered within an accredited department using megavoltage photons from a linear accelerator (typical energies 4–6 MV) as an unbroken course. (R) Cambridge University Press 2016-05 /pmc/articles/PMC4873911/ /pubmed/27841122 http://dx.doi.org/10.1017/S0022215116000530 Text en © JLO (1984) Limited 2016 http://creativecommons.org/licenses/by/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Guidelines
Lund, V J
Clarke, P M
Swift, A C
McGarry, G W
Kerawala, C
Carnell, D
Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title_full Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title_fullStr Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title_full_unstemmed Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title_short Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
title_sort nose and paranasal sinus tumours: united kingdom national multidisciplinary guidelines
topic Guidelines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873911/
https://www.ncbi.nlm.nih.gov/pubmed/27841122
http://dx.doi.org/10.1017/S0022215116000530
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