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Tubulin is a molecular target of the Wnt-activating chemical probe

BACKGROUND: In drug discovery research, cell-based phenotypic screening is an essential method for obtaining potential drug candidates. Revealing the mechanism of action is a key step on the path to drug discovery. However, elucidating the target molecules of hit compounds from phenotypic screening...

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Detalles Bibliográficos
Autores principales: Fukuda, Yasunori, Sano, Osamu, Kazetani, Kenichi, Yamamoto, Koji, Iwata, Hidehisa, Matsui, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873989/
https://www.ncbi.nlm.nih.gov/pubmed/27207629
http://dx.doi.org/10.1186/s12858-016-0066-9