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Management of massive diffuse alveolar hemorrhage in a child with systemic lupus erythematosus

Diffuse alveolar hemorrhage (DAH) from systemic lupus erythematosus (SLE) is a rare but potentially life-threatening condition. We report the case of a 14-year-old female with SLE who developed hypoxia and shock secondary to severe alveolar hemorrhage. She was successfully managed by placement on ex...

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Detalles Bibliográficos
Autores principales: Kimura, Dai, Shah, Samir, Briceno-Medina, Mario, Sathanandam, Shyam, Haberman, Brent, Zhang, Jie, Myers, Linda, Kumar, TK Susheel, Knott-Craig, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874015/
https://www.ncbi.nlm.nih.gov/pubmed/27213047
http://dx.doi.org/10.1186/s40560-015-0076-5
Descripción
Sumario:Diffuse alveolar hemorrhage (DAH) from systemic lupus erythematosus (SLE) is a rare but potentially life-threatening condition. We report the case of a 14-year-old female with SLE who developed hypoxia and shock secondary to severe alveolar hemorrhage. She was successfully managed by placement on extracorporeal membrane oxygenation (ECMO) followed by emergent pulmonary lobectomy and medical treatment including high-dose methylprednisolone, cyclophosphamide, intravenous immunoglobulin, and plasmapheresis.