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What is memory? The present state of the engram
The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous “excitations”, whose preci...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874022/ https://www.ncbi.nlm.nih.gov/pubmed/27197636 http://dx.doi.org/10.1186/s12915-016-0261-6 |
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| author | Poo, Mu-ming Pignatelli, Michele Ryan, Tomás J. Tonegawa, Susumu Bonhoeffer, Tobias Martin, Kelsey C. Rudenko, Andrii Tsai, Li-Huei Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles |
| author_facet | Poo, Mu-ming Pignatelli, Michele Ryan, Tomás J. Tonegawa, Susumu Bonhoeffer, Tobias Martin, Kelsey C. Rudenko, Andrii Tsai, Li-Huei Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles |
| author_sort | Poo, Mu-ming |
| collection | PubMed |
| description | The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous “excitations”, whose precise physical nature and consequences were out of reach of the biology of his day. Neuroscientists now have the knowledge and tools to tackle this question, however, and this Forum brings together leading contemporary views on the mechanisms of memory and what the engram means today. |
| format | Online Article Text |
| id | pubmed-4874022 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-48740222016-05-21 What is memory? The present state of the engram Poo, Mu-ming Pignatelli, Michele Ryan, Tomás J. Tonegawa, Susumu Bonhoeffer, Tobias Martin, Kelsey C. Rudenko, Andrii Tsai, Li-Huei Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles BMC Biol Forum The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous “excitations”, whose precise physical nature and consequences were out of reach of the biology of his day. Neuroscientists now have the knowledge and tools to tackle this question, however, and this Forum brings together leading contemporary views on the mechanisms of memory and what the engram means today. BioMed Central 2016-05-19 /pmc/articles/PMC4874022/ /pubmed/27197636 http://dx.doi.org/10.1186/s12915-016-0261-6 Text en © Poo et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Forum Poo, Mu-ming Pignatelli, Michele Ryan, Tomás J. Tonegawa, Susumu Bonhoeffer, Tobias Martin, Kelsey C. Rudenko, Andrii Tsai, Li-Huei Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles What is memory? The present state of the engram |
| title | What is memory? The present state of the engram |
| title_full | What is memory? The present state of the engram |
| title_fullStr | What is memory? The present state of the engram |
| title_full_unstemmed | What is memory? The present state of the engram |
| title_short | What is memory? The present state of the engram |
| title_sort | what is memory? the present state of the engram |
| topic | Forum |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874022/ https://www.ncbi.nlm.nih.gov/pubmed/27197636 http://dx.doi.org/10.1186/s12915-016-0261-6 |
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