Sterilization techniques for biodegradable scaffolds in tissue engineering applications

Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on diffe...

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Detalles Bibliográficos
Autores principales: Dai, Zheng, Ronholm, Jennifer, Tian, Yiping, Sethi, Benu, Cao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874054/
https://www.ncbi.nlm.nih.gov/pubmed/27247758
http://dx.doi.org/10.1177/2041731416648810
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author Dai, Zheng
Ronholm, Jennifer
Tian, Yiping
Sethi, Benu
Cao, Xudong
author_facet Dai, Zheng
Ronholm, Jennifer
Tian, Yiping
Sethi, Benu
Cao, Xudong
author_sort Dai, Zheng
collection PubMed
description Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on different sterilization techniques including heat, chemical, irradiation, and other novel sterilization techniques for various biodegradable scaffolds. Comparisons of these techniques, including their sterilization mechanisms, post-sterilization effects, and sterilization efficiencies, are discussed.
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spelling pubmed-48740542016-05-31 Sterilization techniques for biodegradable scaffolds in tissue engineering applications Dai, Zheng Ronholm, Jennifer Tian, Yiping Sethi, Benu Cao, Xudong J Tissue Eng Review Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on different sterilization techniques including heat, chemical, irradiation, and other novel sterilization techniques for various biodegradable scaffolds. Comparisons of these techniques, including their sterilization mechanisms, post-sterilization effects, and sterilization efficiencies, are discussed. SAGE Publications 2016-05-17 /pmc/articles/PMC4874054/ /pubmed/27247758 http://dx.doi.org/10.1177/2041731416648810 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Dai, Zheng
Ronholm, Jennifer
Tian, Yiping
Sethi, Benu
Cao, Xudong
Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title_full Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title_fullStr Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title_full_unstemmed Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title_short Sterilization techniques for biodegradable scaffolds in tissue engineering applications
title_sort sterilization techniques for biodegradable scaffolds in tissue engineering applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874054/
https://www.ncbi.nlm.nih.gov/pubmed/27247758
http://dx.doi.org/10.1177/2041731416648810
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AT sethibenu sterilizationtechniquesforbiodegradablescaffoldsintissueengineeringapplications
AT caoxudong sterilizationtechniquesforbiodegradablescaffoldsintissueengineeringapplications

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