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Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874277/ https://www.ncbi.nlm.nih.gov/pubmed/27257563 http://dx.doi.org/10.1097/GOX.0000000000000595 |
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author | Gualdi, Giulio Monari, Paola Pelizzari, Laura Cammalleri, Daniele Calzavara-Pinton, Piergiacomo |
author_facet | Gualdi, Giulio Monari, Paola Pelizzari, Laura Cammalleri, Daniele Calzavara-Pinton, Piergiacomo |
author_sort | Gualdi, Giulio |
collection | PubMed |
description | The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized at both feet and treated for many years successfully with immunosuppressive agents. For cardiological dysfunction, systemic therapy was reduced to low dosage of steroids with an increase of ulcerations (5 × 2 cm). So we decided to perform the nested graft on the plantar region. After the surgical procedure, all the grafted ulcers healed, and at a 4-month follow-up, no signs of lichen sclerosus were present. |
format | Online Article Text |
id | pubmed-4874277 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-48742772016-06-02 Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease Gualdi, Giulio Monari, Paola Pelizzari, Laura Cammalleri, Daniele Calzavara-Pinton, Piergiacomo Plast Reconstr Surg Glob Open Case Report The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized at both feet and treated for many years successfully with immunosuppressive agents. For cardiological dysfunction, systemic therapy was reduced to low dosage of steroids with an increase of ulcerations (5 × 2 cm). So we decided to perform the nested graft on the plantar region. After the surgical procedure, all the grafted ulcers healed, and at a 4-month follow-up, no signs of lichen sclerosus were present. Wolters Kluwer Health 2016-03-07 /pmc/articles/PMC4874277/ /pubmed/27257563 http://dx.doi.org/10.1097/GOX.0000000000000595 Text en Copyright © 2016 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. |
spellingShingle | Case Report Gualdi, Giulio Monari, Paola Pelizzari, Laura Cammalleri, Daniele Calzavara-Pinton, Piergiacomo Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title | Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title_full | Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title_fullStr | Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title_full_unstemmed | Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title_short | Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease |
title_sort | nested graft for acral lichen sclerosus of the feet: a surgical treatment for an inflammatory disease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874277/ https://www.ncbi.nlm.nih.gov/pubmed/27257563 http://dx.doi.org/10.1097/GOX.0000000000000595 |
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