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Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease

The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized a...

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Autores principales: Gualdi, Giulio, Monari, Paola, Pelizzari, Laura, Cammalleri, Daniele, Calzavara-Pinton, Piergiacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874277/
https://www.ncbi.nlm.nih.gov/pubmed/27257563
http://dx.doi.org/10.1097/GOX.0000000000000595
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author Gualdi, Giulio
Monari, Paola
Pelizzari, Laura
Cammalleri, Daniele
Calzavara-Pinton, Piergiacomo
author_facet Gualdi, Giulio
Monari, Paola
Pelizzari, Laura
Cammalleri, Daniele
Calzavara-Pinton, Piergiacomo
author_sort Gualdi, Giulio
collection PubMed
description The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized at both feet and treated for many years successfully with immunosuppressive agents. For cardiological dysfunction, systemic therapy was reduced to low dosage of steroids with an increase of ulcerations (5 × 2 cm). So we decided to perform the nested graft on the plantar region. After the surgical procedure, all the grafted ulcers healed, and at a 4-month follow-up, no signs of lichen sclerosus were present.
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spelling pubmed-48742772016-06-02 Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease Gualdi, Giulio Monari, Paola Pelizzari, Laura Cammalleri, Daniele Calzavara-Pinton, Piergiacomo Plast Reconstr Surg Glob Open Case Report The “nested graft” is an innovative and well-defined surgical technique used for chronic wound healing that induces the de-senescence of fibroblasts in the wound bed. We report a case of a 76-year-old man affected by plantar chronic wounds because of acral lichen sclerosus and atrophicus localized at both feet and treated for many years successfully with immunosuppressive agents. For cardiological dysfunction, systemic therapy was reduced to low dosage of steroids with an increase of ulcerations (5 × 2 cm). So we decided to perform the nested graft on the plantar region. After the surgical procedure, all the grafted ulcers healed, and at a 4-month follow-up, no signs of lichen sclerosus were present. Wolters Kluwer Health 2016-03-07 /pmc/articles/PMC4874277/ /pubmed/27257563 http://dx.doi.org/10.1097/GOX.0000000000000595 Text en Copyright © 2016 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Case Report
Gualdi, Giulio
Monari, Paola
Pelizzari, Laura
Cammalleri, Daniele
Calzavara-Pinton, Piergiacomo
Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title_full Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title_fullStr Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title_full_unstemmed Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title_short Nested Graft for Acral Lichen Sclerosus of the Feet: A Surgical Treatment for an Inflammatory Disease
title_sort nested graft for acral lichen sclerosus of the feet: a surgical treatment for an inflammatory disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874277/
https://www.ncbi.nlm.nih.gov/pubmed/27257563
http://dx.doi.org/10.1097/GOX.0000000000000595
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