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Sun proteins and Dpy19l2 forming LINC-like links are critical for spermiogenesis

Summary: In this response to Pasch et al.’s (2015) discovery that Sun4 is essential for sperm head formation, the authors highlight that like Sun4, Dpy19l2 has a likely LINK-like function and that it also plays a crucial role in spermiogenesis and male infertility.

Detalles Bibliográficos
Autores principales: Ray, Pierre F., Coutton, Charles, Arnoult, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874352/
https://www.ncbi.nlm.nih.gov/pubmed/27142332
http://dx.doi.org/10.1242/bio.016626
Descripción
Sumario:Summary: In this response to Pasch et al.’s (2015) discovery that Sun4 is essential for sperm head formation, the authors highlight that like Sun4, Dpy19l2 has a likely LINK-like function and that it also plays a crucial role in spermiogenesis and male infertility.