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VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis
Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell responses that control vascular development. Multiple isoforms of VEGF-A can elicit differential signal transduction and endoth...
Autores principales: | Fearnley, Gareth W., Smith, Gina A., Abdul-Zani, Izma, Yuldasheva, Nadira, Mughal, Nadeem A., Homer-Vanniasinkam, Shervanthi, Kearney, Mark T., Zachary, Ian C., Tomlinson, Darren C., Harrison, Michael A., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874356/ https://www.ncbi.nlm.nih.gov/pubmed/27044325 http://dx.doi.org/10.1242/bio.017434 |
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