Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma

In an effort to identify the functional alleles associated with hepatocellular carcinoma (HCC), we investigated 152 genes found in the 4q21-25 region that exhibited loss of heterozygosity (LOH). A total of 2,293 pairs of primers were designed for 1,449 exonic and upstream promoter regions to amplify...

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Detalles Bibliográficos
Autores principales: Lin, Yung-Feng, Li, Ling-Hui, Lin, Chih-Hung, Tsou, Mei-Hua, Chuang, Ming-Tai Kiffer, Wu, Keh-Ming, Liao, Tsai-Lien, Li, Jian-Chiuan, Wang, Wei-Jie, Tomita, Angela, Tomita, Beverly, Huang, Shiu-Feng, Tsai, Shih-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874628/
https://www.ncbi.nlm.nih.gov/pubmed/27203079
http://dx.doi.org/10.1371/journal.pgen.1006051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874628/
https://www.ncbi.nlm.nih.gov/pubmed/27203079
http://dx.doi.org/10.1371/journal.pgen.1006051

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